chamberlain-neurochemical-2006

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Chamberlain et al. administered a noradrenaline uptake inhibitor to one group, a serotonin reuptake inhibitor (citalopram) to another, and compaed both to a control group.

Those with inhibited serotonin reuptake (and therefore stronger serotoninergic activity) performed worse on a task where they were asked to choose either a red or green stimulus. One (green/red) is correct, one (red/green) is wrong. When the participant selects a stimulus, they will be told whether or not they were correct, but this answer has a 20% chance to be misleading. One of the differences in the citalopram group is that they were more likely to change their estimate when told they were wrong - and so were more frequently misled by the feedback.

https://pubmed.ncbi.nlm.nih.gov/16469930/

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